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Isaiah 1:16

Wash you, make yourself clean; put away the evil of your doings from before my eyes; cease to do evil;
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Augustine of Hippo

AD 430
So present yourself to such a head as a body worthy of him, to such a bridegroom as a worthy bride.… This is the bride of Christ, without stain or wrinkle. Do you wish to have no stain? Do what is written.… Do you wish to have no wrinkle? Stretch yourself on the cross. You see, you do not only need to be washed but also to be stretched, in order to be without stain or wrinkle; because by the washing sins are removed, while by the stretching a desire is created for the future life, which is what Christ was crucified for. - "Sermon 341.13"

Augustine of Hippo

AD 430
He [the one who is fasting] will wash his face, that is, cleanse his heart, with which he will see God, no veil being interposed on account of the infirmity contracted from squalor; but being firm and steadfast, inasmuch as he is pure and guileless.… From the squalor, therefore, by which the eye of God is offended, our face is to be washed. - "Sermon on the Mount 2.42"
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Bede

AD 735
Now they ask wrongly who persevere in sins and ill-advisedly entreat the Lord to forgive them the sins they do not at all forgive [others]. He condemns such as these through [the mouth of] Isaiah.… Still, having regard for such as these, Isaiah shows in what way they can obtain what they plead for when he goes on. - "Homilies on the Gospels 2.14"
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George Leo Haydock

AD 1849
Wash. Interiorly. (Calmet) He seems to allude to baptism. (Eusebius) (Theodoret)
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Gregory The Dialogist

AD 604
He who does not keep innocence of life after weeping, neglects to be clean after washing; and those are not clean after washing who, though not ceasing to weep for their sins, yet commit again what has to be wept for. - "Pastoral Care 3.30"
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Hippolytus of Rome

AD 235
Beloved, see how the prophet predicted the washing of baptism. For the person who comes to the washing of regeneration with faith, renounces the devil, joins himself to Christ, denies the enemy, confesses that Christ is God, puts off the bondage and puts on the adoption is the one who emerges from the baptism “as bright as the sun,” shining with beams of righteousness and, most importantly, returns a child of God and a joint heir with Christ. - "On the Theophany 10"
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Jerome

AD 420
“You are being washed; be clean.” Instead of the sacrifices named above and holocausts and the abundance of fat and the blood of bulls and goats, instead of incense and new moons, the sabbath feast day and fastings, festivals and other solemnities, the religion of the gospel is what pleases me, that you would be baptized in my blood through the washing of regeneration, which alone is able to remove sins. For no one will enter the kingdom of heaven who has not been reborn from water and the spirit. And the Lord himself, ascending to the Father, said, “Go and teach all the nations, baptizing them in the name of the Father, and the Son, and the Holy Spirit.” - "Commentary on Isaiah 1.1.16"

John Chrysostom

AD 407
Let us accept the medicine that obliterates our failures. Repentance is not what is spoken in words but what is confirmed by deeds, the repentance that obliterates the filth of impiety from the heart.… Why “before my eyes”? Because the eyes of people see differently, and the eye of God sees differently.… “Do not adulterate repentance with pretense,” he says, “but, before my eyes, which examine what is secret, reveal the fruits of repentance.” - "Homilies on Repentance and Almsgiving 7.3.10"
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John Chrysostom

AD 407
I say this, for in the prophet’s words he does not mean bathing by water—the Jewish method of purification—but the purifying of the conscience. Let us also, then, be clean. - "Homilies on the Gospel of John 70"
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John Chrysostom

AD 407
Let us become as clean as is possible. Let us wash away our sins. And the prophet teaches us how to wash them away, saying, “Wash yourselves, make yourselves clean, put away from my eyes the evil of your souls.” … See that we must first cleanse ourselves, and then God cleanses us. He first said, “Wash yourselves, make yourselves clean,” and then said, “I will make you white.” … The power of repentance is then tremendous as it makes us white as snow and wool, even though sin had stained our souls. - "On the Epistle to the Hebrews 12.4"
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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