He shall enter also into the glorious land, and many countries shall be overthrown: but these shall escape out of his hand, even Edom, and Moab, and most of the children of Ammon.
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Aquinas Study Bible
AD 2017
This refers to the Antichrist, asserting that he shall first fight against the king of the South, or Egypt, and shall afterwards conquer Libya and Ethiopia, for these constitute the three broken horns about which we read previously. And then he shall come to the land of Israel, and many cities or provinces shall be given into his hands. Edom, Moab... The Antichrist also is going to leave Idumaea, Moab, and the children of Ammon (i.e., Arabia) untouched, for the saints are to flee thither to the deserts. (St. Jerome)
They say that in his haste to fight Ptolemy, the king of the South, Antiochus left untouched the Idumaeans, Moabites, and Ammonites, who dwelt to the side of Judaea, lest he should make Ptolemy the stronger by engaging in some other campaign. The Antichrist also is going to leave Idumaea, Moab, and the children of Ammon (i.e., Arabia) untouched, for the saints are to flee thither to the deserts.