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Isaiah 6:7

And he laid it upon my mouth, and said, Lo, this has touched your lips; and your iniquity is taken away, and your sin purged.
All Commentaries on Isaiah 6:7 Go To Isaiah 6

Ambrose of Milan

AD 397
Tell me, then, whoever you are who deny the divinity of the Holy Spirit. The Spirit could not be liable to sin, who rather forgives sin. Does an angel forgive? Does an archangel? Certainly not, but the Father alone, the Son alone and the Holy Spirit alone [can forgive sins]. Now one is obviously able to avoid that which he has power to forgive. But perhaps someone will say that the seraph said to Isaiah, “Behold, this has touched your lips and shall take away your iniquities and purge away your sins.” Shall take away, he says, and shall purge, not I will take away, but that fire from the altar of God, that is, the grace of the Spirit. For what else can we piously understand to be on the altar of God but the grace of the Spirit? Certainly not the wood of the forests or the soot and coals. Or what is so in accordance with piety as to understand according to the mystery that it was revealed by the mouth of Isaiah that everyone should be cleansed by the passion of Christ, who as a coal according to the flesh burnt up our sins, as you read in Zechariah: “Is not this a brand snatched from the fire? Now Joshua was clothed in filthy garments.”
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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