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Genesis 48:5

And now your two sons, Ephraim and Manasseh, who were born unto you in the land of Egypt before I came unto you into Egypt, are mine; as Reuben and Simeon, they shall be mine.
All Commentaries on Genesis 48:5 Go To Genesis 48

Cyril of Alexandria

AD 444
And we the last became the first through faith, and the nation of the Gentiles inherited the glory of the firstborn. They obtained that honor through obedience and faith. And Christ himself testified about them by saying, “A people whom I did not know served me, with their ear’s hearing they obeyed me.” Even though we were born from a mother of different kinds, since the church was called among different nations, Christ is sufficient for us as a mediator, who unites us to God the Father, and ascribes some to the lot of the saints, and gives them the right glory and declares us to be a holy generation. But see how through Jacob’s love for Joseph he placed the sons of Joseph among his own sons. And so we are also beloved in Christ, and after we were born again through him in a spiritual generation, we are received by the Father, as I have already said, and added to the saints who preceded us. In fact, if we have been called children of God the Father, we also must be under the power and control of the one who led us and united us to him, that is, Christ. See how the holy Jacob received Ephraim and Manasseh among his own sons: “As for the offspring born to you after them, they will be yours.” You understand now that even though we are called children of God, nonetheless we will be children of Christ. And this is, I believe, what he says to the Father in another passage: “Those whom you gave me from the world were yours, and you gave them to me, and I have been glorified in them.” ,
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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