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Genesis 25:22

And the children struggled together within her; and she said, If it be so, why am I thus? And she went to inquire of the LORD.
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Ephrem The Syrian

AD 373
“God blessed Isaac,” and Isaac prayed for Rebekah, who was barren. After twenty years God heard him, and she conceived. Her sons struggled together within her womb. She went to inquire of the Lord, and it was told her, “Two nations are in your womb,” that is, the Edomite and Hebrew nations. To whom did she go to inquire? It was to Melchizedek that she went to inquire, as we mentioned above in the genealogy of Melchizedek. She returned quickly because of the pangs that were striking her, and she gave birth to Esau and Jacob.
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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