Genesis 25:21

And Isaac entreated the LORD for his wife, because she was barren: and the LORD was entreated of him, and Rebekah his wife conceived.
All Commentaries on Genesis 25:21 Go To Genesis 25

John Chrysostom

AD 407
One question is worth raising initially: If she and her husband were conspicuous for their good life and both concerned for chaste living, why was she barren? We cannot find fault with their life or say barrenness was the result of sin. To grasp the full extent of this remarkable circumstance, remember that it was not only herself who was barren but also the good man’s mother, Sarah; and not only his mother but also his daughterinlaw—I mean Jacob’s wife Rachel. What is the meaning of this gallery of sterile people? All were good people, all virtuous, all given testimony by God; of them he said, “I am the God of Abraham, the God of Isaac and the God of Jacob.” And blessed Paul says, “Hence God is not ashamed to be called their God.” There is great commendation of them in the New Testament; great praise of them in the Old. In each case they were distinguished and remarkable men, yet all had barren wives. They spent a long period in a childless condition. So whenever you see a man and wife of virtuous life experiencing childlessness, whenever you see pious people devoted to religion yet childless, don’t think it is the result of sin. After all, many reasons for God’s designs are beyond our understanding, and we ought to thank God for everything and brand as wicked only those living in sin, not those without children. It frequently happens, in fact, that God works things for our good without our realizing the reason for what happens. Hence in every case we should marvel at his wisdom and praise his ineffable love.
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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