And Cain went out from the presence of the LORD, and dwelt in the land of Nod, on the east of Eden.
All Commentaries on Genesis 4:16 Go To Genesis 4
Ephrem The Syrian
The land of Nod is so called because it was the land in which Cain wandered about in fear and trembling. But the land also received a second curse when God said, “When you till the earth it shall no longer yield to you its strength.” .