Professing themselves to be wise, they became fools,
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Ambrosiaster
AD 400
They imagined that they were wise because they thought they had explored the natural sciences, investigating the courses of the stars and the quantities of the elements, while rejecting the God who made them. Therefore they are fools, for if these things are worthy of praise, how much more is their Creator! Commentary on Paul’s Epistles.
Having some high opinion of themselves and not being patient enough to go the way that God had commanded them, they were immersed in a way of thinking which made no sense.
For having some great conceit of themselves, and not enduring to go the way which God had commanded them, they were plunged into the reasonings of senselessness (1 manuscript διανοίας). And then to show and give in outline, what a rueful surge it was, and how destitute of excuse, he goes on to say.
But (as I have said) pardon may be granted to those who are ignorant and do not own themselves to be wise; but it cannot be extended to those who, while they profess.
they bore a certain likeness and appearance