Matthew 16:21

From that time forth began Jesus to show unto his disciples, how that he must go unto Jerusalem, and suffer many things of the elders and chief priests and scribes, and be killed, and be raised again the third day.
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George Leo Haydock

AD 1849
From that time Now when the apostles firmly believed that Jesus was the Messias, and the true Son of God, he saw it necessary to let them know he was to die an infamous death on the cross, that they might be disposed to believe that mystery; (Witham) and that they might not be too much exalted with the power given to them, and manifestation made to them. (Haydock)

Jerome

AD 420
But that none should suppose that this is only any explanation, and not an evangelic interpretation, what follows explains the reasons of His forbidding them to preach Him at that time; “Then began Jesus to show unto his disciples that he must needs go unto Jerusalem, and suffer many things of the elders and Scribes, and Chief Priests, and be put to death, and rise again the third day. "The meaning is; Then preach Me when I shall have suffered these things, for it will be of no avail that Christ be preached publicly, and His Majesty spread abroad among the people, when after a little time they shall see Him scourged and crucified.

John Chrysostom

AD 407
But not even so did they understand what He said. For the saying, it is said, was hid from them; Luke 18:34 and they were as in a kind of perplexity, not knowing that He must rise again. Therefore He rather dwells on the difficulties, and enlarges His discourse, that He may open their mind, and they may understand what it can be that He speaks of.

John Chrysostom

AD 407
For what having once had root has afterwards been torn up, if it is again planted, is with difficulty retained among the multitude; but what having been once rooted has continued ever after unmoved, is easily brought on to a further growth. He therefore dwells on these sorrowful things, and repeats His discourse upon them, that He may open the minds of His disciples. He must needs go to Jerusalem, to be put to death indeed in the Jerusalem which is below, but to rise again and reign in the heavenly Jerusalem. But when Christ rose again, and others were risen with Him, they no longer sought the Jerusalem which is beneath, or the house of prayer in it, but that which is above. He suffers many things from the elders of the earthly Jerusalem, that He may be glorified by those heavenly elders who receive His mercies. He rose again from the dead on the third day, that He may deliver from the evil one, and purchase for such as are so delivered this gift, that they be baptized in spirit, soul,...

John Chrysostom

AD 407
Peter was examining the issue by human and earthly reasoning. He thought it disgraceful to Jesus as something unworthy of him. Jesus responded sharply, in effect saying, “My suffering is not an unseemly matter. You are making this judgment with a carnal mind. If you had listened to my teachings in a godly way, tearing yourself away from carnal understanding, you would know that this of all things most becomes me. You seem to suppose that to suffer is unworthy of me. But I say to you that for me not to suffer is of the devil’s mind.” So he repressed Peter’s alarm by contrary arguments. Remember that John, accounting it unworthy of Christ to be baptized by him, was persuaded by Christ to baptize him, saying, “Let it be so now.” So we find Peter as well, forbidding Christ to wash his feet. He is met by the words, “If I do not wash you, you have no part in me.” Here too Jesus restrained him by the mention of the opposite, and by the severity of the reproof he repressed his fear of sufferin...

Theophylact of Ochrid

AD 1107
. To them He foretells the Passion, lest it come upon them unexpectedly and they be scandalized, thinking that He suffered unwillingly and without foreknowing it. When they had heard, in Peter’s confession, that He was the Son of God, then He also revealed the Passion to them. But to the sorrow He adds the joy, that He would rise on the third day.

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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