And he took the blind man by the hand, and led him out of the town; and when he had spit on his eyes, and put his hands upon him, he asked him if he saw anything.
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Ambrose of Milan
AD 397
So too he placed mud upon you, that is, modesty, prudence, and consideration of your frailty…. You went, you washed, you came to the altar, you began to see what you had not seen before. This means: Through the font of the Lord and the preaching of the Lord’s passion, your eyes were then opened. You who seemed before to have been blind in heart began to see the light of the sacraments.
And taking the blind man by the hand, He led him out of the town, i.e, outside of Bethsaida, as is plain from ver22. He led him forth for the same reason that when He was about to heal the deaf and dumb man He took him aside from the multitude. This was, 1st For the sake of prayer, that, being alone, He might collect His thoughts, and unite Himself wholly to God, and pray the more intently and collectedly2To fly from the applause of men, and teach us to do the same3Because the citizens of Bethsaida were unworthy of the miracle of Christ; for although they had seen Him work so many miracles, they would not believe in Him.
And spitting upon his eyes. Fasting spittle does good to the purblind, but does not illuminate those who have actually lost their sight. The saliva, therefore, of Christ was not a natural but a supernatural remedy for blindness, being the instrument by which Christ"s Godhead wrought.
S. Hilarion imitated this miracle by which Christ gave sight to a blind Prayer of Ma...
It may be asked, why our Lord led the man from the multitude before he cured him?
It may be answered, that he did it not to seem to perform his prodigies through vain glory; and thence to teach us to shun the empty praises of men: 2dly, to facilitate recollection, and to give himself to prayer, before he cured the blind man; and lastly, he went out of the city because the inhabitants of Bethsaida had already rendered themselves unworthy of the miracles of Christ. For among them our Saviour had wrought many miracles, yet they would not believe. (St. Matthew xi. 21.) (Tirinus) (Theophylactus)
Dionysius says, that Jesus led him from the multitude to show that if a sinner, figured by the blind man, wishes to be converted from his evil ways, he must first leave all immediate occasions and inducements to sin. (Dionysius)