Luke 17:22

And he said unto the disciples, The days will come, when you shall desire to see one of the days of the Son of man, and you shall not see it.
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Ambrose of Milan

AD 397
He who knows the signs of the coming judgment also knows the end. Why would he not know? He is like flashing lightning, since as the Light, the Son of God illumines the inner part of the heavenly mystery. “In that hour,” it says. He also knows the hour, but he knows it for himself, he does not know it for me. He then suitably asserts that the cause of the flood, fire and of the judgment proceeded from our sins, because God did not create evil, but our actions devised it for themselves. –.
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Bede

AD 735
Or, by the day of Christ He signifies His kingdom, which we hope will come, and He lightly says, one day, because there shall no darkness disturb the glory of that blessed time. It is right then to long for the day of Christ, yet from the earnestness of our longing, let us not vision to ourselves as though the day were at hand. Hence it follows, And they shall say to you, Lohere! and, Lo there!. And he well says, that lightens out of the one part under heaven, because the judgment will be given under the heaven, that is, in the midst of the air, as the Apostle says, We shall be caught up together with them in the clouds. But if the Lord shall appear at the Judgment like lightning, then shall no one remain hidden in the deep of his heart, for the very brightness of the Judge pierces through him; we may also take this answer of our Lord to refer to His coming, whereby He comes daily into His Church. For ofttimes have heretics so vexed the Church, by saying that the faith of Christ stands...

Cornelius a Lapide

AD 1637
And He said unto His disciples, The days will come. That Isaiah , the time will come and is now at hand, when for My faith and the preaching of the gospel you will suffer many adversities, persecutions, and distresses; the errors and heresies, moreover, of the innovators; and be oppressed by straits of body and mind, and know not what consolation or counsel to take. Hence you shall seek to see Me, and to consult Me, if only once, but in vain: for after I shall have ascended into heaven, I shall no more appear on earth. Thus the things you now hear from Me you ought to teach, and to console, and to direct, until, at my second coming to judgment, I return to you, that Isaiah , to your successors. Thus He spoke to warn them that they could only come to the kingdom of glory through tribulations, that they might neither fail in heart nor fall from the faith. So Theophylact, Euthymius, Titus , Bede, and others.

Cyril of Alexandria

AD 444
He now speaks to the holy disciples as his true companions. He says, “The days will come when you will desire to see one of the days of the Son of man, and will not see it.” … He would have them prepared for all that can cause people grief. He wants them ready to endure patiently so that approved they may enter the kingdom of God. He warns them that before his coming from heaven at the consummation of the world, tribulation and persecution will precede him. They will wish to see one of the days of the Son of man, such as those when they were still going around with Christ and speaking with him. Commentary on Luke, Homily

Cyril of Alexandria

AD 444
That they might know that he was about first to undergo his saving passion, abolish death by the death of his flesh, put away the sin of the world, destroy the ruler of this world, ascend to the Father and in due time appear to judge the world in righteousness, he says that he must first suffer many things. Commentary on Luke, Homily
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Cyril of Alexandria

AD 444
At the end time of the world, he will not descend from heaven obscurely or secretly, but with godlike glory and as dwelling in the light which no one can approach. He declared that his coming will be like the lightning. He was born indeed in the flesh of a woman, to fulfill the dispensation for our sakes. For this reason, he emptied himself, made himself poor, and no longer showed himself in the glory of the Godhead. The season and the necessity of the dispensation summoned him to this humiliation. After his resurrection from the dead, ascension into heaven, and enthronement with God the Father, he will descend again. He will not descend with his glory withdrawn or in the lowliness of human nature. In the majesty of the Father with the companies of the angels guarding him, he will stand before him as God and Lord of all. He will come as the lightning, and not secretly. Commentary on Luke, Homily

Cyril of Alexandria

AD 444
Now His disciples supposed that He would go to Jerusalem, and would at once make a manifestation of the kingdom of God. To rid them therefore of this belief, He informs them that it became Him first to suffer the Life-giving Passion, then to ascend to the Father and shine forth from above, that He might judge the world in righteousness. Hence He adds, But first must he suffer many things, and be rejected of this generation.
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Eusebius of Caesarea

AD 339
As if he said, If at the coming of Antichrist, his fame shall bespread abroad, as though Christ had appeared, go not out, nor follow him. For it cannot be that He who was once seen on earth, shall any more dwell in the corners of the earth. It will therefore be he of whom we speak, not the true Christ. For this is the clear sign of the second coming of our Savior, that suddenly the luster of His coming shall fill the whole world; and so it follows, For as the lightning that lightens For He will not appear walking upon the earth, as any common man, but will illuminate our whole universe, manifesting to all men the radiance of His divinity.

George Leo Haydock

AD 1849
To see one day Hereafter, when I shall be no longer visibly among you, you shall heartily wish for one day's conversation with me. (Witham) This verse is addressed to the disciples. He insinuates that he will take from them this corporeal presence, and they shall be exposed to persecution and affliction: then they shall wish to see one day of the Son of man, and shall not be able to obtain it. They shall wish ardently to see him, to entertain themselves with him, and consult him, but shall not have that happiness. This was meant to excite the disciples to profit more of his presence whilst they enjoyed it. (Calmet)

Theophilus of Antioch

AD 184
For their life was then without trouble, for Christ took care of them and protected them. But the time was coming when Christ should be taken away, and they should be exposed to perils, being brought before kings and princes, and then they should long for the first time and its tranquillity.
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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