But we speak wisdom among them that are mature: yet not the wisdom of this world, nor of the princes of this world, that come to nothing:
All Commentaries on 1 Corinthians 2:6 Go To 1 Corinthians 2
John Chrysostom
AD 407
Paul is saying that when he, a man thought to be foolish and a preacher of folly, gets the better of the wise, he overcomes their wisdom, not by foolishness but by a more perfect wisdom. This wisdom is so broad and so great that the other kind appears to be foolishness. True wisdom is the gospel, the means of salvation through the cross of Christ. The perfect are those who believe. They are indeed “perfect,” because they know that all human things are utterly helpless, and therefore they ignore them, being convinced that they have nothing to gain from them. This is what true believers are like.