And the angel came in unto her, and said, Hail, you that are highly favored, the Lord is with you: blessed are you among women.
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Gregory of Nyssa
AD 394
Far different then to the news formerly addressed to the woman, is the announcement now made to the Virgin. In the former, the cause of sin was punished by the pains of childbirth; In the latter, through gladness, sorrow is driven away. Hence the angel not unaptly proclaims joy to the Virgin, saying, Hail.