Jesus, when he had cried again with a loud voice, yielded up his spirit.
All Commentaries on Matthew 27:50 Go To Matthew 27
Hilary of Poitiers
AD 368
De Trin. x. 50: From these words heretical spirits contend either that God the Word was entirely absorbed into the soul at the time it discharged the function of a soul in quickening the body; or that Christ could not have been born man, because the Divine Word dwelt in Him after the manner of aprophetical spirit. As though Jesus Christ was a man of ordinary soul and body, having His beginning then when He began to be man, and thus now deserted upon the withdrawal of the protection of God’s word cries out, “My God, my God, whyhast thou forsaken me?”.
Vinegar is wine, which has turned sour either from neglect, or the fault of the vessel. Wine is the honour of immortality, or virtue. When this then had been turned sour in Adam, He took and drunk it at the hands of the Gentiles. It is offered to Him on a reed and a spunge; that is, He took from the bodies of the Gentiles immortality spoiled and corrupted, and transfused in Himself into amixture of immortality that in us which was spoiled.
Or, He gave up the ghost with a loud voice, in grief that He was not carrying the sins of all men.