Men and brethren, this scripture must needs have been fulfilled, which the Holy Spirit by the mouth of David spoke before concerning Judas, who was guide to them that took Jesus.
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Epiphanius of Cyprus
AD 403
the scripture had to be fulfilled: The Apostles bring to fulfillment what David had stated was to be done.
Therefore, after the resurrection of the Lord, and His assumption into the heavens, being desirous of filling up the number of the twelve apostles, and in electing into the place of Judas any substitute who should be chosen by God, thus addressed those who were present: "Men
the scripture had to be fulfilled: Always he comforts them by the prophecies. So does Christ on all occasions. In the very same way, he shows here that no strange thing had happened, but what had already been foretold.
which the Holy Spirit spoke beforehand by the mouth of David: He does not say, David, but the Spirit through him. See what kind of doctrine the writer has at the very outset of the book. Do you see, that it was not for nothing that I said in the beginning of this work, that this book is the Polity of the Holy Spirit?
the scripture had to be fulfilled: Not that scripture forced the event, but it did mention an event that would happen: This scripture says: He who ate my bread has lifted his heel against me.(Psalm 41:9)
who was the leader of those who apprehended Jesus: Judas had agreed with the chief priests to betray Christ, he looked for an opportunity to deliver him without disturbing the people. And because some of the crowd might resist, he took a band of soldiers, not from the Jews, but from the governor. In this way, no one would dare to resist because they would see the marks of legitimate authority. Further, some Jews might resist out of zeal for the law, especially because Christ was being taken by Gentiles. For this reason Judas took some servants or officers from the chief priests and the Pharisees. (John 18:3)