That good thing which was committed unto you keep by the Holy Spirit who dwells in us.
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Basil the Great
AD 379
If we offer glory to God in the Spirit, we mean that the Spirit enables us to fulfill the requirements of true religion. According to this usage, then, we say we are in the Spirit, but it is not objectionable for someone to testify, “the Spirit of God is in me, and I offer glory because his grace has given me the wisdom to do so.” The words of Paul are appropriate: “I think that I have the Spirit of God,” and “guard the truth that has been entrusted to you by the Holy Spirit who dwells within us.”
Keep the good (doctrine) deposited or committed in trust to thee. This is different, though the word be the same, from what he spoke of, ver. 12. There he mentioned what he had committed and deposited in the hands of God; here he speaks of what God hath committed, and deposited in the hands of Timothy, after it was delivered to him by St. Paul and the other preachers of the gospel: that is, he speaks of the care Timothy must take to preserve the same sound doctrine, and to teach it to others. See 1 Timothy vi. 20. (Witham)
That good thing which was committed unto you keep,— how?— by the Holy Ghost which dwells in us. For it is not in the power of a human soul, when instructed with things so great, to be sufficient for the keeping of them. And why? Because there are many robbers, and thick darkness, and the devil still at hand to plot against us; and we know not what is the hour, what the occasion for him to set upon us. How then, he means, shall we be sufficient for the keeping of them? By the Holy Ghost; that is if we have the Spirit with us, if we do not expel grace, He will stand by us. For, Except the Lord build the house, they labor in vain that build it. Except the Lord keep the city, the watchman wakes but in vain. Psalm 127:1 This is our wall, this our castle, this our refuge. If therefore It dwells in us, and is Itself our guard, what need of the commandment? That we may hold It fast, may keep It, and not banish It by our evil deeds.
Before all things, keep that truth which is committed to your trust, the holy Word of faith by which you have been taught and instructed. And let no weeds of heresy grow up among you, but preserve the heavenly seed pure and sincere, that it may yield a great harvest to the master, when he comes to demand account of our lives. He shall reward us according to our deeds, when the righteous shall shine forth as the sun, but darkness and everlasting shame shall cover the sinners.