2 Thessalonians 2:3

Let no man deceive you by any means: for that day shall not come, except there come the falling away first, and that man of sin be revealed, the son of perdition;
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Ambrosiaster

AD 400
He says this so that they will not be upset by their own lack of caution and be led astray into the worship of the Devil.
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Augustine of Hippo

AD 430
He who speaks on his own seeks his own glory. This will be that one who is called the Antichrist, “exalting himself,” as the apostle says, “above all that is called God and that is worshiped.” Indeed, the Lord, announcing that he would seek his own glory, not the glory of the Father, said to the Jews, “I have come in the name of my Father, and you have not received me; another will come in his own name, this one you will receive.” He signified that they would receive the Antichrist, who would seek the glory of his own name, puffed up, hollow, and so not enduring but in fact ruinous. But our Lord Jesus Christ offered us a great example of humility.

Augustine of Hippo

AD 430
No one can doubt that Paul is here speaking of Antichrist, telling us that the day of judgment (which he calls the day of the Lord) will not come without the prior coming of a figure whom he calls the Apostate, meaning, of course, an apostate from the Lord God. And if this appellation can rightly be attached to all the ungodly, how much more to him! There is, however, some uncertainty about the “temple” in which he is to take his seat. Is it the ruins of the temple built by King Solomon, or actually in a church? For the apostle would not say “the temple of God” if he meant the temple of some idol or demon. For that reason some people would have it that Antichrist means here not the leader himself but what we may call his whole body, the multitude, that is, of those who belong to him, together with himself, their leader…. For myself I am much astonished at the great presumption of those who venture such guesses. .

Basil the Great

AD 379
In truth, both of our ears rang on learning of the shameless and inhuman heresy of those who persecuted you. They had no regard for age, nor for the labors of a life well spent, nor for the affection of the people. On the contrary, they tortured and dishonored bodies, handed them over to exile and plundered whatever property they were able to find, not fearing the censure of men nor foreseeing the fearful requital of the just Judge…. But, along with these considerations, there came this thought also: The Lord has not entirely abandoned his churches, has he? And this is not the last hour, is it? Is apostasy finding an entrance through them, in order that now the impious one may be revealed, “the son of perdition, who opposes and is exalted above all that is called God, or that is worshiped”? But if the trial is transitory, bear it, noble champions of Christ…. For if all creation is destroyed and the scheme of the world is altered, what wonder is it if we also, being a part of creation, ...

Cyril of Jerusalem

AD 386
Such is Paul’s account. And we have reached the “falling away.” Men, that is, have fallen away from the true faith. Some proclaim the identity of Father and Son. Others dare to assert that one should believe Christ has come into existence out of nonexistence. Formerly heretics were quite evident, but now the church is full of masked heretics. For men have deserted the truth and want to have their ears tickled. Make a plausible case, and everyone is ready to listen to you. Talk of changing one’s life, and everyone deserts you. The majority have fallen away from the sound doctrines and are readier to choose what is bad than to prefer what is good. So there you have the “falling away,” and the coming of the enemy is to be expected next. Meanwhile, he has begun to send out his forerunners here and there, so that the spoil may be prepared for him when he comes. Therefore, brothers, look to yourselves. Watch over your souls carefully.

George Leo Haydock

AD 1849
First, lib. xx. de Civ. Dei. chap. 19. t. 7. p. 597. Nov. edit., where he says: For my part, I own myself altogether ignorant what the apostle means by these words; but I shall mention the suspicions of others, which I have read, or heard. Then he sets down the exposition concerning the Roman empire. He there calls that a suspicion and conjecture, which others say is an apostolical tradition. In like manner the ancient fathers are divided, as to the exposition of the words of the sixth and seventh verse, when it is said you know what hindereth; some understand that antichrist must come first. Others, that the before mentioned apostacy, or falling off from the Church, must happen before. And when St. Paul says, (ver. 7.) that he who now holdeth, do hold; some expound it, let him take care at the time of such trials, to hold, and preserve the true faith to the end. When the expositions are so different, as in this place, whosoever pretends to give a literal translation ought never to add...

Hippolytus of Rome

AD 235
But as, in accordance with the train of our discussion, we have been constrained to come to the matter of the days of the dominion of the adversary, it is necessary to state in the first place what concerns his nativity and growth; and then we must turn our discourse, as we have said before, to the expounding of this matter, viz., that in all respects the accuser and son of lawlessness
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John Chrysostom

AD 407
Here Paul discusses the Antichrist and reveals great mysteries. What is the “falling away”? He calls him Apostasy; soon he will destroy many and make them fall away…. And he calls him “the man of sin.” For he shall commit numberless evils and shall cause others to do them. But Paul calls him “the son of perdition,” because he is also to be destroyed. But who is he? Satan? By no means. Rather he is a man in whom Satan fully works. For he is a man…. For he will not introduce idolatry but will be a kind of opponent to God. He will abolish all the gods and will order men to worship him instead of God. He will be seated in the temple of God, not that in Jerusalem only, but also in every church.

John Chrysostom

AD 407
Here he discourses concerning the Antichrist, and reveals great mysteries. What is the falling away? He calls him Apostasy, as being about to destroy many, and make them fall away. So that if it were possible, He says, the very Elect should be offended. From Matthew 24:24 And he calls him the man of sin. For he shall do numberless mischiefs, and shall cause others to do them. But he calls him the son of perdition, because he is also to be destroyed. But who is he? Is it then Satan? By no means; but some man, that admits his fully working in him. For he is a man. And exalts himself against all that is called God or is worshipped. For he will not introduce idolatry, but will be a kind of opponent to God; he will abolish all the gods, and will order men to worship him instead of God, and he will be seated in the temple of God, not that in Jerusalem only, but also in every Church. Setting himself forth, he says; he does not say, saying it, but endeavoring to show it. For he will perform gr...

Justin Martyr

AD 165
O unreasoning men! understanding not what has been proved by all these passages, that two advents of Christ have been announced: the one, in which He is set forth as suffering, inglorious, dishonoured, and crucified; but the other, in which He shall come from heaven with glory, when the man of apostasy,
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Shepherd of Hermas

AD 150
Happy ye who endure the great tribulation that is coming on, and happy they who shall not deny their own life.
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Tertullian of Carthage

AD 220
Well, but who is the man of sin, the son of perdition "who must first be revealed before the Lord comes; "who opposeth and exalteth himself above all that is called God, or that is worshipped; who is to sit in the temple of God, and boast himself as being God? "
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Tertullian of Carthage

AD 220
According to our view, he is the Antichrist; as it is taught to us in both the ancient and the new prophecies, and especially by the Apostle John (1Jn 4:1-3), who says that “already many false prophets are gone out into the world,” the fore-runners of Antichrist, who deny that Christ is come in the flesh, and do not acknowledge Jesus (to be the Christ), meaning in God the Creator. (Against Marcion 2 Thess)
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The Didache

AD 100
And then shall appear the world-deceiver
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Thietland of Einsiedeln

AD 1000
Such is the saying of the Lord, "If someone should say to you, 'Behold, here is the Christ,' or 'there,' do not believe it (Mt 24:23)."
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Victorinus of Pettau

AD 303
Paul the apostle says: "Except there come a falling away first, and the man of sin shall appear, the son of perdition; and the adversary who exalted himself above all which is called God, or which is worshipped."
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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