1 Timothy 4:1

Now the Spirit speaks expressly, that in the latter times some shall depart from the faith, giving heed to deceitful spirits, and doctrines of demons;
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Alexander of Alexandria

AD 250
Now concerning their blasphemous assertion who say that the Son does not perfectly know the Father, we need not wonder. Indeed, having once purposed in their mind to wage war against Christ, they impugn also these words of his, “As the Father knows Me, even so know I the Father.” … Moreover, concerning these very men, warnings are not wanting to us, for the Lord foretold, “Take heed that you are not deceived: for many shall come in My name, saying, I am Christ; and the time draws near: do not go therefore after them.” Paul, too, having learned these things from the Savior, wrote, “In the latter times some shall depart from the faith, giving heed to seducing spirits, and doctrines of devils which turn away from the truth.”

Alexander of Alexandria

AD 250
Paul, too, having learnt these things from the Saviour, wrote, "In the latter times some shall depart from the faith, giving heed to seducing spirits, and doctrines of devils which turn away from the truth."
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Ambrose of Milan

AD 397
As for me, indeed, would that they might have a will to hear, that they might believe—to hear with true love and meekness, as men seeking what is true and not assailing all truth. For it is written that we pay no heed to “endless fables and genealogies, which do rather raise disputes than set forward the godly edification, which is in faith. But the aim of the charge is love from a pure heart, and a good conscience, and faith unfeigned, whence some have erred and betaken themselves to empty babbling. For they are desirous of being teachers of the law, without understanding the words they say, nor the things whereof they speak with assurance.” In another place also the same apostle says, “Avoid foolish and ignorant questionings.” Such men, who sow disputes—that is to say, heretics—the apostle bids us leave alone. Of them he says in yet another place that “certain shall depart from the faith, giving heed to deceitful spirits and the doctrines of devils.” –.

Athanasius the Apostolic

AD 373
Therefore it becomes us to watch, lest some deception be conveyed under the clothing of their phrases and they lead some away from the true faith. And if they venture to advance the opinions of Arius, when they see themselves proceeding in a prosperous course, nothing remains for us but to use great boldness of speech. For we are to remember the predictions of the apostle, which he wrote to forewarn us of such heresies and which it becomes us to repeat. For we know that, as it is written, “in the latter times some shall depart from the true faith, giving heed to seducing spirits and doctrines of devils, that turn from the truth.”

Augustine of Hippo

AD 430
The fulfillment of these predictions in the Manichaeans is as clear as day to all that know them and has already been proved as fully as time permits.
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Augustine of Hippo

AD 430
Considering the signs mentioned by Gospel and prophecy which we see happening, would anyone deny that we ought to hope for the coming of the Lord? Manifestly, it is nearer and nearer every day. But the exact span of the nearness, that, as we said, “is not for you to know.” Notice when the apostle said this, “For our salvation is nearer than when we believed. The night is past and the day is at hand,” and look how many years have passed! Yet, what he said was not untrue. How much more probable is it to say now that the coming of the Lord is near when there has been such an increase of time toward the end! Certainly the apostle said, “The Spirit manifestly says that in the last times some shall depart from the faith.” Obviously, those were not yet the times of heretics such as he describes them in the same sentence, but they have now come. According to this, we seem to be in the last times, and the heretics seem to be a warning of the end of the world. .

Clement Of Alexandria

AD 215
Jam de iis, qui matrimonium abhorrent, dicit beatus Paulus: "In novissimis diebus deficient quid am a fide, attendentes spiritibus erroris, et doctrinis daemoniorum, prohibentium nubere, abstinere a cibis.". erte "dicit Spiritus, quod in posterior bus temporibus deficient quid am a fide, attendentes spiritibus erroris, et doctrinis daemoniorum, in hypocrisi falsiloquorum, cauteriatam habentium conscientiam, et prohibentium nubere, abstinere a cibis quos Deus creavit ad participationem cum gratiarum actione fidelibus, et qui agnoverunt veritatem, quod omnis creatura Dei bona est, et nihil est rejiciendum quod sumitur cure gratiarum actione. Sanctificatur enim per verb urn Dei et orationem? "
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Cyril of Jerusalem

AD 386
That the Holy Spirit subsists, lives, speaks and foretells I have told you repeatedly on former occasions. Paul writes clearly to Timothy, “Now the Spirit expressly says that in later times some will depart from the faith.” This we see in the factions of former times and in our own day. How diverse and multiform are the errors of the heretics.
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George Leo Haydock

AD 1849
In the last times. Literally, last days; i.e. hereafter, or in days to come. To spirits of error and doctrines of devils; or, to seducing spirits and doctrines of devils, as in the Protestant translation. The sense must be, that men shall teach false doctrine by the suggestion of the devil. (Witham)
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Hippolytus of Rome

AD 235
Certain will depart from sound doctrine, giving heed to seducing spirits and doctrines of devils, uttering falsehoods in hypocrisy, having their own conscience seared with a hot iron, forbidding to marry, to abstain from meats, which God has created to be partaken of with thanksgiving by the faithful, and those who know the truth; because every creature of God is good, and nothing to be rejected which is received with thanksgiving; for it is sanctified by the word of God and prayer."
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John Chrysostom

AD 407
As those who adhere to the faith are fixed on a safe anchor, so those who fall from the faith can nowhere rest; but after many wanderings to and fro, they are borne at last into the very gulf of perdition. And this he had shown before, saying, that some had already made shipwreck concerning the faith, and now he says, Now the Spirit speaks expressly, that in the latter times some shall depart from the faith, giving heed to seducing spirits. This is said of the Manichæans, the Encratites, and the Marcionites, and the whole of their tribe, that they should hereafter depart from the faith. Do you see that this departure from the faith is the cause of all the evils that follow! But what is expressly? Plainly, clearly, and beyond doubt. Marvel not, he says, if some having departed from the faith still adhere to Judaism. There will be a time, when even those who have partaken of the faith will fall into a worse error, not only with respect to meats, but to marriages, and other such things...
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Justin Martyr

AD 165
There were prophets a very long time ago more ancient than these who are reputed to be philosophers, blessed and righteous and dear to God. They spoke by a divine spirit, and they oracularly predicted future events which are now taking place. They are truly called prophets…. Past events and events now taking place compel us to agree with what was spoken by them. Furthermore they deserved to be believed because of the miracles which they performed, since they were glorifying God the Creator and Father of the universe and they were announcing the Christ coming from him, his Son. The false prophets who were filled with the deceitful and filthy spirit never did nor now do this. They dare to work various supposed miracles in order to impress men, and they glorify the spirits and demons of deceit.

Nicetas of Remesiana

AD 414
How could anyone be silent in regard to the divine authority of the Holy Spirit? The ancient prophets cried out, “These things say the Lord.” When Christ came, he also used this word “say” in his own person, “But I say unto you.” Listen now to what the prophets of the New Testament proclaim. Take the prophet Agabus in the Acts of the Apostles, “Thus says the Holy Spirit.” So, too, Paul to Timothy, “Now the Spirit expressly says …” Power of the Holy Spirit
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Tertullian of Carthage

AD 220
These are “the doctrines” of men and “of demons” that produce for itching ears of the spirit this world’s wisdom. This is what the Lord called “foolishness.” God “chose the foolish things of the world” to confound even philosophy itself. For philosophy is the material of the world’s wisdom, the rash interpreter of the nature and the providence (dispensations) of God.
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Tertullian of Carthage

AD 220
Neither ought their existence to surprise us, for it was foretold that they should come to pass;. What harshness, therefore, is here on our part, if we renounce (communion with) such as do not the will of God? What heresy, if we judge second marriage, as being unlawful, akin to adultery? For what is adultery but unlawful marriage? The apostle sets a brand upon those who were wont entirely to forbid marriage, who were wont at the same time to lay an interdict on meats which God has created. And accordingly (they think) us to have been even then prenoted as "in the latest times departing from the faith, giving heed to spirits which seduce the world, having a conscience inburnt with doctrines of liars."

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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