1 Timothy 2:5

For there is one God, and one mediator between God and men, the man Christ Jesus;
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Ambrose of Milan

AD 397
Let not the venom of Apollinaris flatter itself because it is written, “And in appearance he was found as a man,” for the manhood of Jesus is not thereby denied but confirmed, since elsewhere Paul himself speaks of him as “Mediator of God and men, himself man, Christ Jesus.” It is the customary manner of Scripture so to express itself as we also read in the Gospel, “And we saw his glory—glory as of the onlybegotten of the Father.” As he is there called onlybegotten Son of God, so he is said to be man, and the fullness of humanity that was in him is not denied.

Ambrose of Milan

AD 397
But what is he who is at once the Most High and man, what but “the Mediator between God and man, the man Christ Jesus who gave himself as a ransom for us”? This text indeed refers properly to his incarnation, for our redemption was made by his blood, our pardon comes through his power, our life is secured through his grace. He gives as the Most High; he prays as man. The one is the office of the Creator; the other of a redeemer. Be the gifts as distinct as they may, yet the Giver is one, for it was fitting that our Maker should be our Redeemer. .

Augustine of Hippo

AD 430
It was in order to make the mind able to advance more confidently toward the truth that Truth itself, the divine Son of God, put on humanity without putting off his divinity and built this firm path of faith so that man, by means of the GodMan, could find his way to man’s God. I speak of the “mediator between God and men, himself man, Christ Jesus.” For it is as man that he is the Mediator and as man that he is the way.
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Augustine of Hippo

AD 430
Who can so organize what he does as this man organized what he suffered? But the man, the Mediator of God and man, was the man about whom one reads that it was foretold, “And he is a man and who will know him?” For the men through whom these things happened did know the man of God. For he who was hidden as God was apparent as man. He who was apparent suffered these things. He who was hidden is the very same One who ordered these things. Therefore he saw that all the things were finished which were necessary to be done before he took the vinegar and delivered over his spirit.

Augustine of Hippo

AD 430
Hence we respond to this objection of theirs, which they propose from the gospel, in a way which allows no man to be so lacking in understanding that he thinks we are compelled by this text to believe and confess that the mediator between God and men, the man Christ Jesus, did not have a human soul. In the same way I inquire how they respond to objections so palpable as ours, whereby we show through countless places in the Gospel writings what was narrated of him by the Evangelists, namely, that he was found with feelings that are impossible without a soul.

Augustine of Hippo

AD 430
But how are we reconciled unless what separates us and him is broken? For he says through the prophet, “The Lord’s ear is not dull, that it cannot hear, but your sins separate you and your God.” Therefore, because we are not reconciled unless what is in the middle has been removed and what should be in the middle has been put there—for there is a separating middle, but over against it is a reconciling mediator. The separating middle is sin. The reconciling mediator is the Lord Jesus Christ, “For there is one God and one mediator of God and man, the man Christ Jesus.” And so, in order that the separating wall which is sin may be taken away, that Mediator has come, and the Priest himself has become the sacrifice.

Augustine of Hippo

AD 430
Christ Jesus, himself man, is the true Mediator, for, inasmuch as he took the “form of a slave,” he became “the Mediator between God and men.” In his character as God, he received sacrifices in union with the Father, with whom he is one God. Yet he chose, in his character as a slave, to be himself the sacrifice rather than to receive it, lest any one might take occasion to think that sacrifice could be rendered to a creature. Thus it is that he is both the Priest who offers and the Oblation that is offered.
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Augustine of Hippo

AD 430
Now, we could not be redeemed, even through “the one mediator between God and man, Man himself, Christ Jesus,” if he were not also God. For when Adam was made—being made an upright man—there was no need for a mediator. Once sin, however, had widely separated the human race from God, it was necessary for a mediator, who alone was born, lived and was put to death without sin, to reconcile us to God and provide even for our bodies a resurrection to life eternal—and all this in order that a man’s pride might be exposed and healed through God’s humility.

Bede

AD 735
We have heard from the Gospel reading [commenting on Lk :–], dearly beloved brothers, that when the Redeemer of the world, our Lord and God, Jesus Christ, was about to be born into the world, an edict went out from Caesar Augustus, who then held the highest place with respect to worldly reigns. The edict said that the entire world was to be enrolled. We must not suppose that this happened by chance, but we must understand that it was provided through a most certain divinely arranged plan of this same Redeemer of ours. And, indeed, just as in his divinity the Mediator between God and human beings foresaw the mother of whom he willed to be born when he should so will, so also in his humanity he chose the time when he wished for his nativity. Moreover, he himself granted that this time should be such as he willed, namely, that in a calm among the storm of wars a singular tranquillity of unusual peace should cover the whole world.

George Leo Haydock

AD 1849
One mediator of God and men, the man Christ Jesus: who gave himself a redemption for all. Take all these words together, and we may easily understand in what sense the apostle calls our Saviour Christ, the one or only mediator; that is, he is the only mediator, who at the same time is our Redeemer; the only mediator who could mediate betwixt God, the person offended by sin, and men the offenders; the only mediator who reconciled God to mankind by his incarnation and death, by the infinite price of his blood, by his own merits, independently of the merits of any other. All Catholics allow that the dignity and office of mediator in this sense belongs only to our Redeemer, Jesus Christ, the Son of God, made man to save us. The sense then of this place is, that as there is but one God, who created all, so there is but one mediator, who redeemed all. But yet the name of mediator is not so appropriated to Christ, but that in an inferior and different sense the Angels and saints in heaven, an...
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Gregory of Nyssa

AD 394
By the distinction implied in the word mediator he reveals to us the whole aim of the mystery of godliness. Now the aim is this. Humanity once revolted through the malice of the enemy, and, brought into bondage to sin, was also alienated from the true Life. After this the Lord of the creature calls back to him his own creature and becomes Man while still remaining God, being both God and man in the entirety of the two separate natures. Thus humanity was indissolubly united to God, the man that is in Christ conducting the work of mediation, to whom, by the firstfruits assumed for us, all the lump is potentially united.

Gregory the Theologian

AD 390
O how beautiful and mystical and kind! For to intercede does not imply to seek for vengeance, as is most men’s way (for in that there would be something of humiliation), but it is to plead for us by reason of his mediatorship, just as the Spirit is also said to make intercession for us. For “there is one God, and one mediator between God and men, the man Christ Jesus.” For he still pleads even now as man for my salvation. He continues to wear the body which he assumed, until he makes me divine by the power of his incarnation; although he is no longer known after the flesh—the same as ours, except for sin.

Hippolytus of Rome

AD 235
Now, in order that He might be shown to have together in Himself at once the nature of God and that of man,-as the apostle, too, says: "Mediator between God and men, the man Christ Jesus.
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Ignatius of Antioch

AD 108
And again, "For there is one God, and one Mediator between God and man, the man Christ Jesus; ". Said also that "there is one Mediator between God and men.". Nor were they ashamed of the incarnation and the passion. For what says
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Irenaeus of Lyons

AD 202
And therefore in the last times the Lord has restored us into friendship through His incarnation, having become "the Mediator between God and men; "
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Isaac of Syria

AD 700
May attention to the economy of God which ministered to those of former times be reckoned by you as precious medicine for weak eyes. Let the memory of it stay with you at all times of the day. Meditate, apply your mind, and learn wisdom from it, that you may be able to receive into your soul with honor the memory of the greatness of God and find eternal life for yourself in Christ Jesus, the Mediator between God and mankind and the Uniter in his two natures.
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John Chrysostom

AD 407
He says that “there is one God,” that is, not as some say, many, and that he has sent his Son as mediator, thus giving proof that he desires that all be saved. But is not the Son God? Most truly he is. Why then does he say, “One God”? To distinguish the one God from idols, not from the Son.
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John Chrysostom

AD 407
He had before said, to come to the knowledge of the truth, implying that the world is not in the truth. Now he says, that there is one God, that is, not as some say, many, and that He has sent His Son as Mediator, thus giving proof that He will have all men to be saved. But is not the Son God? Most truly He is; why then does he say, One God? In contradistinction to the idols; not to the Son. For he is discoursing about truth and error. Now a mediator ought to have communion with both parties, between whom he is to mediate. For this is the property of a mediator, to be in close communion with each of those whose mediator he is. For he would be no longer a mediator, if he were connected with one but separated from the other. If therefore He partakes not of the nature of the Father, He is not a Mediator, but is separated. For as He is partaker of the nature of men, because He came to men, so is He partaker of the nature of God, because He came from God. Because He was to mediate between t...
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Lucius Caecilius Firmianus Lactantius

AD 320
He was therefore both God and man, being placed in the middle between God and man. From which the Greeks call Him Me sites,
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Tertullian of Carthage

AD 220
Valentinus, indeed, on the strength of his heretical system, might consistently fantasize a spiritual flesh for Christ. Any who refused to believe that that flesh was human might then pretend it to be anything he liked. This pretense characterizes all heresies. For if his flesh was not human and was not born of man, I do not see of what substance Paul himself spoke, when he said “The man Christ Jesus is the one mediator between God and man.”
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Tertullian of Carthage

AD 220
The Apostle Paul likewise says: "The man Christ Jesus is the one Mediator between God and man.". Designated, as He is, "the Mediator. Wherever it may be, it is in safe keeping in God's presence, through that most faithful "Mediator between God and man, (the man) Jesus Christ". In respect of that nature, in which He was Spirit, reserving for the flesh the appellation "Son of Man. "In like manner, again, the apostle calls Him "the Mediator between God and Men"
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Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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