1 Corinthians 16:9

For a great and effective door is opened unto me, and there are many adversaries.
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Ambrosiaster

AD 400
Paul made it clear that he was staying at Ephesus because he had found hearts there who were thirsting for the grace of God, and in them he could quickly instill the mystery of Christ. But because the devil is always restless and hostile to those who long for God, he adds that his enemies there are many. For the more they sought after the faith, the more there were adversaries who contradicted them and fought against the teaching of the Lord. Commentary on Paul’s Epistles.

Cornelius a Lapide

AD 1637
A great door . . . is opened unto me. A great opportunity of preaching the Gospel and of converting many. So Ambrose.

George Leo Haydock

AD 1849
A gate is opened to me, large and evident; that is, a fair and good occasion of labouring to convert many, where there are many adversaries. (Witham) The work of God is carried on by the power of the cross, and in the midst of contradictions and persecutions. If we suffer this to damp our courage, we forget that we are ministers of a crucified master, and ought to wear his livery.

John Chrysostom

AD 407
It was precisely because the opportunities were so great that Paul had so many adversaries. The devil is always active when he risks losing his booty.

John Chrysostom

AD 407
Now if it was great, how could there be adversaries? Why on this very account the adversaries were many, because men's faith was great; because the entrance was great and wide. But what means, A great door? There are many prepared to receive the faith, many ready to approach and be converted. There is a spacious entrance for me, things being now come to that point that the mind of those approaching is at its prime for the obedience of the faith. On this account, vehement was the blast of the breath of the devil, because he saw many turning away from him. You see then on both accounts it was needful for him to stay; both because the gain was abundant, and because the struggle was great. And herewith also he cheered them up, namely, by saying, that henceforth the word works every where and springs up readily. And if there be many who plot against it, this also is a sign of the advance of the Gospel. For at no time does that evil demon wax fierce, except on seeing his goods made spo...

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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