Luke 22:15

And he said unto them, With desire I have desired to eat this passover with you before I suffer:
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Basil the Great

AD 379
We should eat the body and drink the blood of the Lord as a commemoration of the Lord’s obedience unto death. They who live might then no longer live for themselves but to him who died for them and rose again.

Cyprian of Carthage

AD 258
If we deny to those who are about to enter on the warfare the blood of Christ? Or how do we make them fit for the cup of martyrdom, if we do not first admit them to drink, in the Church, the cup of the Lord

Cyril of Alexandria

AD 444
Christ is also within us in another way by means of our partaking in the sacrifice of bloodless offerings, which we celebrate in the churches. We received from him the saving pattern of the rite, as the blessed Evangelist plainly shows us in the passage that has just been read. He tells us that Jesus took a cup, gave thanks and said, “Take this, and divide it with one another.” His giving thanks meant his speaking to God the Father in the manner of prayer. Christ signified to us that he, so to speak, shares and takes part in the Father’s good pleasure in granting us the lifegiving blessing that was given to us then. Every grace and every perfect gift comes to us from the Father by the Son in the Holy Spirit. This act, then, was a useful pattern for us of the prayer that should be offered whenever the grace of the mystical and lifegiving sacrifice is about to be spread before him by us. Accordingly, we are accustomed to do this. First, offering up our thanksgivings and joining in our pr...

Cyril of Alexandria

AD 444
He says, “I will no longer come near to such a Pascha as this,” one that consisted in the typical eating. A lamb of the flock was killed to be the type of the true Lamb until it is fulfilled in the kingdom of God, that is, until the time has appeared in which the kingdom of heaven is preached. This is fulfilled in us, who honor the worship that is superior to the law, even the true Pascha. A lamb of the flock does not sanctify those who are in Christ. Christ sanctifies us. He was made a holy sacrifice for us, by the offering of bloodless offerings and the mystical giving of thanks, in which we are blessed and enlivened. He became for us the living bread that came down from heaven, and he gives life to the world. Commentary on Luke, Homily

Ephrem The Syrian

AD 373
He said, “I will not drink again of this fruit of the vine until the kingdom of my Father,” to show that he foresaw his imminent departure from them. He said, “until the kingdom of my Father,” that is, until his resurrection. Simon Peter revealed in the Acts of the Apostles, “After his resurrection, during a period of forty days, we ate with him and we drank, on this first day of the week. This agrees with what he had said, “They will not taste death before they see the kingdom of God,” and after six days that was accomplished. Commentary on Tatian’s Diatessaron

George Leo Haydock

AD 1849
With desire I have desired: literally, with a desire have I desired. The repetition expresseth a great and earnest desire. (Witham)

Irenaeus of Lyons

AD 202
When he came to his passion, he wanted to declare to Abraham and those with him the good news of the opening of the inheritance. After he gave thanks while holding the cup and then drank from it … he promised that he would again drink of the produce of the vine with his disciples. Christ thus showed the inheritance of the earth, in which the new produce of the vine is drunk, and the physical resurrection of his disciples. The new flesh that rises again is the same that received the new cup. He cannot be understood as drinking the produce of the vine when established on high with his own, somewhere above the heavens. Those who drink it are not only spirits, because it belongs to flesh and not to spirit to receive the drink of the vine. .

John Chrysostom

AD 407
Again, in another place Christ said, “I have greatly desired to eat this Pasch with you.” Why then did he say “this Pasch” even though at other times he had observed this feast with them? Why then? Because the cross would follow this Pasch. And again he said, “Father, glorify your Son so that your Son may glorify you.” To be sure, in many places we find him foretelling the Passion, desiring that it come to pass and saying that this was the reason he had come into the world.

Tertullian of Carthage

AD 220
, by which He so earnestly desired to eat the pass over with His disciples. How earnestly, therefore, does He manifest the bent of His soul: "With desire I have desired to eat this passover with you before I suffer.". we have proved from the sacrament of the bread and the cup

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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