John 17:16

They are not of the world, even as I am not of the world.
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Cornelius a Lapide

AD 1637
They are not of the world. He repeats what He had said before about the world, to show why the Father should care for and protect them, viz, because they had left the world, and given themselves wholly to the worship and protection of Christ.

Cyril of Alexandria

AD 444
By these words He indicates once more, and makes clear to us, the reason why He requires to ascend to God the Father, and why so to do becomes Him, while He is still our Mediator, and High Priest, and Advocate, according to the Holy Scripture; and shows us that it is in order that, if at any time we encounter failure, or miss the straight path in thought or action, or are assailed by unexpected perils or buffeted by the tempest of the devil's malice, He may approach His Father on our behalf in His appropriate character as Mediator; and join with Him in granting good gifts to those who are worthy. For it would well become Him so to do, as He is God by Nature. Those then, He says, who have received Thy Word, O Father, through Me, show forth My Likeness in themselves and are conformed to the pattern of Thine own Son, who, like Him, pass unscathed through the ocean of the world's wickedness, and have shown themselves foreigners and strangers to the love of pleasure in this life, and every ...

John Chrysostom

AD 407
How then says He in another place, Which You gave Me out of the world; Yours they were? John 17:6 There He speaks of their nature; here of wicked actions. And He puts together a long encomium of them; first, that they were not of the world; then, that the Father Himself had given them; and that they had kept His word; and that on this account they were hated. And if He says, As I am not of the world, be not troubled; for the as is not here expressive of unvarying exactness. For as, when in the case of Him and the Father the as is used, a great Equality is signified, because of the Relationship in Nature; so when it is used of us and Him, the interval is great, because of the great and infinite interval between the respective natures. For if He did no sin, neither was guile found in His mouth 1 Peter 2:22, how could the Apostles be reckoned equal to Him? What is it then that He says, They are not of the world? They look to another world, they have nothing common with earth, but have bec...

Knowing this first, that no prophecy of the scripture is of any private interpretation. - 2 Peter 1:20

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