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Isaiah 6:5

Then said I, Woe is me! for I am undone; because I am a man of unclean lips, and I dwell in the midst of a people of unclean lips: for my eyes have seen the King, the LORD of hosts.
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Cassiodorus Senator

AD 585
We must especially follow the commandments, and signing our lips with the seal of the cross we must pray to the Lord that he may cleanse our mouths, which are disfigured with human foulness. - "Exposition of the Psalms 141.8"

Cassiodorus Senator

AD 585
By “mouth” [or lips] is meant the hidden region of the heart, from which God’s praise is efficaciously sung. So he rightly proclaims after the forgiveness of his sin that his lips will be opened and that his mouth can announce the praise of the Lord. - "Exposition of the Psalms 5.17"

George Leo Haydock

AD 1849
Peace. It is proper for sinners to do so, Ecclesiasticus xv. 9. The prophet was grieved that he was unworthy to join in the acclamation of the Seraphim, and had reason to fear death, Genesis xvi. 13., and Exodus xxxiii. 20. He finds himself less able to speak than before, like Moses, Exodus iv. 10., and vi. 12.

Gregory The Dialogist

AD 604
Purity of heart and simplicity are most precious in the sight of Almighty God, who is fully pure and simple in nature. Set apart from the ways of the world, the servants of God are strangers to its vain talk and thus avoid disturbing and soiling their minds in idle conversation.… We are drawn downward by mingling in continual conversation with people of the world. It is with good reason that Isaiah, after seeing the Lord, the King of hosts, accuses himself of this very fault. In a spirit of repentance he says, “Woe is me, because I have held my peace; because I am a man of unclean lips.” And why are his lips unclean? Because, as he explains immediately, “I dwell in the midst of a people that has unclean lips.” Grieving that his own lips are unclean, he shows us that he contracted this defilement by living among a people that had unclean lips. To take part in the talk of worldly people without defiling our own heart is all but impossible. If we permit ourselves to discuss their affairs ...

Jerome

AD 420
According to the Hebrew, Isaiah cries out in anguish and says, “Woe is me because I have held my peace, because I am a man of unclean lips and I dwell in the midst of a people that has unclean lips, and I have seen with my eyes the Lord of hosts!” Because of his virtues, he deserved to enjoy the sight of God, and, because of his awareness of his sins, he confessed that his lips were unclean. Not because he had said anything that was contrary to the will of God, but because he had held his peace, deterred either by fear or modesty, and because he had not exercised the prerogative of a prophet, of condemning a sinful nation. When we, who flatter the rich and accept sinful persons, rebuke sinners, is it for the sake of base gain? Unless, perhaps, we speak with complete frankness to those whose wealth we stand in need of. We may act otherwise; we may refrain from every type of sin, but, if we keep silent about the truth, we are certainly committing a sin. - "Against the Pelagians 2.24"

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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