Neither let him who is in the field return back to take his clothes.
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Theophylact of Ochrid
To suggest the utter inevitability of the calamities, He says that one must flee without turning back, and without taking any thought for what is in the houses, neither clothing nor any other possessions. Some say that the "abomination of desolation" means the Antichrist who will come at the time of the desolation of the world and the destruction of the churches and will sit in the temple. They also interpret these things as follows: he who is on the housetop, that is, he who has attained the heights of the virtues, let him not come down from that height in to order to take with him the things of the body. For the house of the soul is the body. But he must also depart from the field, that is, from earthly things, for the field is earthly life. Neither must we return to take our clothing, which is the former wickedness which we have put off.