Romans 1:3

Concerning his Son Jesus Christ our Lord, who was made of the descendants of David according to the flesh;
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Ambrosiaster

AD 400
“Concerning his Son.” It was fitting, since God promised his own Son to the world, that he should promise him through great men, so that from them it might be known how very powerful the one who was being preached was and so that he might include his future coming in the Holy Scriptures. And what is preached by the Holy Scriptures cannot be shown to be false. “Who was descended from the seed of David according to the flesh.” He who was the Son of God according to the Holy Spirit (that is, according to God, because God is Spirit and without any doubt he is holy), is said to have been made the Son of God according to the flesh by Mary, as it is written: “The Word became flesh.” Christ Jesus is both Son of God and Son of Man. As he is truly God, so also he is truly man. For he would not be truly man if he were not of flesh and soul. Otherwise he would be incomplete. For although he was the Son of God in eternity, he was not known by the creation until, when God wanted him to be revealed for the salvation of mankind, he made him visible and corporeal, because God wanted him to be known through his power to cleanse humans from their sins by overcoming death in the flesh. Therefore he was made of the seed of David. As he was born a king from God before the beginning of time, so also he would acquire birth from a king according to the flesh, being made from a virgin by the work of the Holy Spirit, i.e., born. Thus by the reverence reserved for him because of this fact, he who by his birth was distinguished from the law of nature would be recognized as being more than a man. This had been predicted by Isaiah the prophet: “Behold a virgin will conceive in her womb.” Hence when the newborn child appeared to be worthy of honor, a certain providence of God was discerned concerning a future visitation of the human race. Commentary on Paul’s Epistles.
2 mins

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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