2 Timothy 4:17

However the Lord stood with me, and strengthened me; that by me the preaching might be fully known, and that all the Gentiles might hear: and I was delivered out of the mouth of the lion.
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Eusebius of Caesarea

AD 339
Story has it that the apostle, after defending himself, was again sent upon the ministry of preaching and coming a second time to the same city met death by martyrdom under Nero. While he was being held in prison, he composed the second epistle to Timothy, at the same time indicating that his first defense had taken place and that martyrdom was at hand.

George Leo Haydock

AD 1849
The Lord stood All agree that Nero is here meant by the lion. St. Chrysostom thinks that St. Paul was set at liberty after this first justification of his conduct, but that having afterwards converted the cupbearer of Nero, he was by him beheaded. (St. Chrysostom, hom. x. p. 611.) But the Lord assisted and fortified me on this occasion by a vision, in which he assured me that he would prolong my life for the more perfect preaching of the gospel. (Bible de Vence) The times predicted by the apostle in this epistle, (ver. 3. and 4.) are now arrived; and the warnings he gives to Timothy and to all preachers of the word, should be sedulously attended to: preach the word: be instant in season and out of season; reprove, entreat, rebuke with all patience and doctrine. There will arrive a time when men will not bear sound doctrine; eager in the extreme to hear what flatters, they will have recourse to a variety of teachers not lawfully sent or ordained, calculated to tickle their ears: Assen...

John Chrysostom

AD 407
He had fallen into the very jaws of the lion. For he calls Nero a lion from his ferocity and the violent and daring character of his government.

John Chrysostom

AD 407
Notwithstanding the Lord stood with me, and strengthened me. Though deserted by man, God does not permit him to suffer any harm. He strengthened me, he says, that is, He gave me boldness in speaking. He suffered me not to sink. That by me the preaching might be fully known. That is, might be fulfilled. Observe his great humility. He does not say He strengthened me as deserving of His gift, but that the preaching, with which I was entrusted, might be fully known. As if any one should wear a purple robe and a diadem, and to that circumstance should owe his safety. And that all the Gentiles might hear. What is this? That the luster of the Gospel, and the care of His Providence for me, might be known to all. And I was delivered out of the mouth of the lion.

John of Damascus

AD 749
So that everything may be revealed through preaching. Not by force, but as he said, through preaching, as if he was bearing a purple garment and a crown (see John 19:2), and because of them he was dilivered up. By "lion" he means Nero.

Knowing this first, that no prophecy of the scripture is of any private interpretation - 2 Peter 1:20

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